How to Cook Pork Tenderloin in the Oven

Oven roasted pork tenderloin is one of my favorite answers to the “What am I making for dinner?” question. The brown sugar and spice rub forms a flavorful caramelized crust, while the pork stays tender and juicy inside.

I’ve been sharing dependable, family-friendly recipes on Momcrieff since 2011, and this is exactly the kind of dinner I rely on myself. It uses everyday seasonings, cooks quickly, and looks impressive enough to serve when company comes over.

If you love simple, easy-to-make dinners, check out my 3 Ingredient Pork Chop Marinade for another delicious weeknight meal. I also have an Overnight Pork Chop Marinade that's also easy! If you want a change from pork, this easy Roasted Chicken with Rosemary is another simple but delicious main course recipe.

Why I Love This Pork Tenderloin in the Oven Recipe

• Quick oven dinner: This oven roasted pork tenderloin is ready in about 40 minutes, making it practical for both weeknight dinners and company.
• Flavorful crust: The brown sugar and simple seasonings create a caramelized crust with plenty of flavor without making the pork hot or overly spicy.
• Tender and juicy: Learning how to cook pork tenderloin in the oven is easy when you use a meat thermometer. Removing it at 145°F helps prevent this lean cut from becoming dry.
• A recipe I rely on: I’ve made plenty of pork tenderloin recipes over the years, and this is the kind I return to because it uses familiar seasonings and consistently turns out well.
• Easy cleanup: The pork is seared and then baked in the same oven-safe skillet, which means fewer dishes to wash after dinner.

Ingredients for Baked Pork Tenderloin

This easy oven-baked pork tenderloin recipe uses simple ingredients you likely already have in your kitchen. Below is what you'll need to make it.

• Pork tenderloin: A typical two-pound package contains two tenderloins. This lean, tender cut of pork cooks quickly and is ideal for oven roasting.
• Brown sugar: Helps create the flavorful, caramelized crust on the outside of the pork.
• Chili powder: Adds depth and mild spice without making the pork tenderloin hot.
• Garlic powder: Provides savory garlic flavor and blends easily into the dry rub.
• Onion powder: Adds another layer of savory flavor to the seasoning mixture.
• Smoked paprika: Gives the pork a subtle smoky flavor. Regular paprika can be substituted.
• Cooking oil: Use a small amount to sear the seasoned pork tenderloins before placing them in the oven.

How to Cook Pork Tenderloin in the Oven

Preheat oven to 375°F. You can line the baking sheet with aluminum foil for easy cleanup.

Step 1
While the oven heats up, pat your pork tenderloin dry with paper towels. This step helps to remove any excess moisture, ensuring that your pork can get a nice, crispy exterior.

Step 2
In a small bowl, mix together brown sugar, garlic powder, onion powder, chili powder, and smoked paprika. Rub this seasoning blend generously over the pork tenderloin, making sure it’s evenly distributed.

Step 3
Using a small amount of oil, sear the tenderloins for about 2 - 3 minutes per side over medium-high heat until all sides are lightly browned.

Step 4
If you use an oven-safe skillet, place it in the oven and roast it for 15 - 20 minutes. If you don't have an oven-safe skillet, transfer to a small baking sheet and roast for the same amount of time.

Bake for 20-25 minutes or until the internal temperature reaches 145°F. If you have a meat thermometer, this is the best way to ensure your pork is cooked to perfection. Keep an eye on it towards the end of the cooking time to avoid overcooking.

Step 4: Rest and slice
Once your pork is done, remove it from the oven and let it rest for about 5 minutes before slicing. Resting allows the juices to redistribute inside the meat, ensuring every slice is tender and juicy. Slice it against the grain for the best texture.

FAQ's

How to Store Baked Pork Tenderloin

If you have leftovers, store your pork tenderloin in an airtight container in the fridge for up to 3-4 days. When reheating, slice the pork and heat it in a skillet over medium heat for a few minutes until warmed through.

You can also store leftovers in the freezer for up to 2-3 months if well wrapped. To reheat from frozen, let it thaw in the fridge overnight and then warm it in the oven or a skillet as above.

Other Easy Pork Recipes

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